474266-82-5Relevant academic research and scientific papers
Dual effect of synthetic aminoglycosides: Antibacterial activity against Bacillus anthracis and inhibition of anthrax lethal factor
Fridman, Micha,Belakhov, Valery,Lee, Lac V.,Liang, Fu-Sen,Wong, Chi-Huey,Baasov, Timor
, p. 447 - 452 (2007/10/03)
Defence against bioterrorism: Recent events have created an urgent need for therapeutic strategies to treat anthrax, an infectious disease caused by the toxigenic bacterium Bacillus anthracis. A new class of aminoglycosides (see picture) are powerful inhi
Reexamination of neomycin B degradation: Efficient preparation of its CD and D rings as protected glycosyl donors
Wu, Baogen,Yang, Jun,He, Yun,Swayze, Eric E.
, p. 3455 - 3458 (2007/10/03)
(matrix presented) The degradation of neomycin B was reexamined, and a novel protocol was established to prepare the properly masked neomycin CD ring as a glycol donor in excellent yield. Glycosylation of the CD ring with glycol acceptors provided a facil
