474274-00-5

Upstream product

• 84487-47-8 2-methyl-6-(cyclopent-2'-en-1'-yl)aniline 
• 235779-09-6 6-(cyclopent-1-en-1-yl)-2-methyl-aniline 
• 410538-58-8 ethyl N-[6-methyl-2-(cyclopent-1-enyl)phenyl]carbamate 

Relevant academic research and scientific papers

Synthesis of 3,1-benzoxazines from N-substituted ortho-(cycloalk-1-enyl or alk-2-en-2-yl)anilines

New derivatives of 3,1-benzoxazine have been synthesized by the cyclization of RCO-substituted at the nitrogen atom (R = OEt, Me, NH2) ortho-(cycloak-1-enyl or alken-l-yl)anilines under mild conditions.

Synthesis of 2′-bromo-8-methylspiro(4H-3,1-benzooxazine-4,1′-cyclopentan)-2(1H)-o ne and 2-amino-2′-bromo-8-methylspiro(4H-3,1-benzooxazine-4,1′-cyclopentane ) from 6-(cyclopent-1-enyl)-2-methylaniline

The reaction of 6-(cyclopent-1-enyl)-N-ethoxycarbonyl-2-methylaniline with Br2 or its reaction with NH3 followed by the reaction with Br2 afforded 2′-bromo-8-methyl-spiro(4H-3,1-benzooxazine-4,1′-cyclopentan)-2(1H)- one and 2-amino-2′-bromo-8-methyl-spiro(4H-3,1-benzooxazine-4,1′-cyclopentan e), respectively.