474295-87-9

Upstream product

• 177966-65-3 methyl (3S)-3-amino-3-(4-hydroxyphenyl)propanoate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 474295-86-8 3-tert-butoxycarbonylamino-3-(4-dimethylcarbamoyloxy-phenyl)-propionic acid methyl ester 
• 474295-85-7 methyl (3S)-3-{[(tert-butoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate 

Downstream Products

• 444646-39-3 [1-(4-dimethylcarbamoyloxy-phenyl)-3-(4-nitro-phenoxy)-propyl]-methyl-carbamic acid tert-butyl ester 
• 474295-88-0 [1-(4-dimethylcarbamoyloxy-phenyl)-3-(4-nitro-phenoxy)-propyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

BENZYLAMINE ANALOGUE

A compound of the formula (I): [wherein R1 represents a C1-C6 alkyl group etc., R2 and R3 are the same or different and represent a hydrogen atom etc., Ra represents a C1-C6 alkyl group etc., Arom represents an aryl group etc., A represents a C1-C6 alkylene group, E represents a single bond, an oxygen atom, a sulfur atom etc., X1 and X2 are the same or different and represent an oxygen atom or a sulfur atom] or a pharmacologically acceptable salt or ester thereof.

Design and synthesis of dual inhibitors of acetylcholinesterase and serotonin transporter targeting potential agents for Alzheimer's disease.

Highly efficient acetylcholinesterase (AChE) and serotonin transporter (SERT) dual inhibitors, (S)-4 and (R)-13 were designed and synthesized on the basis of the hypothetical model of AChE active site. Both compounds showed potent inhibitory activities against AChE and SERT. [structure: see text]