4744-51-8 Usage
Uses
Used in Pharmaceutical Industry:
2,5-Pyrazinediethanol is used as an impurity in the production of Clavulanic acid for its impact on the metabolic processes of Streptomyces clavuligerus, the bacteria responsible for producing Clavulanic acid. The presence of high concentrations of Clavulanic acid, but not its degradation products, including 2,5-Pyrazinediethanol, decreases glycerol consumption and oxygen uptake rates in the bacterial cultures, which can be crucial for optimizing the production process and yield of the antibiotic.
Additionally, understanding the role and effects of 2,5-Pyrazinediethanol as an impurity can help in the development of more efficient and effective methods for producing Clavulanic acid, potentially leading to advancements in the pharmaceutical industry and the treatment of various bacterial infections.
Check Digit Verification of cas no
The CAS Registry Mumber 4744-51-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,4 and 4 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4744-51:
(6*4)+(5*7)+(4*4)+(3*4)+(2*5)+(1*1)=98
98 % 10 = 8
So 4744-51-8 is a valid CAS Registry Number.
4744-51-8Relevant articles and documents
Studies on the Hydrolysis of Clavulanic Acid
Finn, Malcolm J.,Harris, Michael A.,Hunt, Eric,Zomaya, Iskander I.
, p. 1345 - 1349 (2007/10/02)
1-Amino-4-hydroxybutan-2-one (14) has been identified as one of the major products from the hydrolysis of clavulanic acid in acidic, alkaline, or neutral solution.In alkaline or neutral solution, the amino ketone (14) is converted into other products, including two pyrazines, 2,5-bis(2-hydroxyethyl)pyrazine and 3-ethyl-2,5-bis(2-hydroxyethyl)pyrazine.A rationale for the formation of these products is discussed.
