474426-99-8

Upstream product

• 474426-79-4 Acetic acid (2S,3S,4S,5R,6S)-4,5,6-triacetoxy-2-phenylcarbamoyl-tetrahydro-pyran-3-yl ester 
• 474426-72-7 acetic 1,2,3,4-tetra-O-acetyl-β-D-glucopyranuronic anhydride 
• 62133-77-1 1,2,3,4-tetra-O-acetyl-β-D-glucopyranuronic acid 

Relevant academic research and scientific papers

The synthesis of cyclic imidates from amides of glucuronic acid and investigation of glycosidation reactions

The synthesis of novel cyclic glycosyl imidates and an investigation of their potential as donors in glycosidation reactions is described. The results show that 1,2-cis glycosides obtained from the reactions of glycosyl acetates or cyclic imidates, each d

Synthesis of α-glucuronic acid and amide derivatives in the presence of a participating 2-acyl protecting group

(graph presented) Participating acyl groups located at C-2 in glucosyl and related donors generally promote formation of 1,2-trans-glycosides. Reactions of some glucuronic acid donors with TMSN3/SnCl4 or ROH/SnCl4 gave only the 1,2-cis-glycoside. The stereoselectivity is consistent with participation of the C-6 group. The methodology was used for the synthesis of a Kdn2en mimetic with the α-configuration.