474555-68-5

Basic information

• Product Name: 8-oxo-7H-2-phenylpyrimido[5,4-c]pyridazin-6-thione
• CAS NO: 474555-68-5
• Molecular Weight: 256.288
• Mol File: 474555-68-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-oxo-7H-2-phenylpyrimido[5,4-c]pyridazin-6-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 8-oxo-7H-2-phenylpyrimido[5,4-c]pyridazin-6-thione(474555-68-5)
• EPA Substance Registry System: 8-oxo-7H-2-phenylpyrimido[5,4-c]pyridazin-6-thione(474555-68-5)

Safety Data

• Hazardous Substances Data: 474555-68-5(Hazardous Substances Data)

Upstream product

• 122-51-0 orthoformic acid triethyl ester 
• 14985-77-4 4-hydroxy-5-phenylazo-6-methylpyrimid-2-thione 

Downstream Products

• 5655-01-6 9-deazahypoxanthine 

Relevant articles and documents

Facile synthesis of 9-substituted 9-deazapurines as potential purine nucleoside phosphorylase inhibitors.

A facile synthesis of 9-substituted 9-deazapurines as potential inhibitors of purine nucleoside phosphorylase has been achieved by the direct Friedel-Crafts aroylation or arylmethylation of 9-deazapurines using trifluoromethanesulfonic acid as catalyst. The aroylated 9-deazapurines could be transformed into the corresponding 9-aryimethyl derivatives by the Wolff-Kishner reaction. A novel synthesis of 9-deazahypoxanthine was also developed by treatment of 4-hydroxy-5-phenylazo-6-methylpyrimidin-2-thione with triethyl orthoformate in trifluoroacetic acid (TFA) to yield 8-oxo-7H-2-phenylpyrimido[5,4-c]pyridazin-6-thione followed by Raney nickel reduction.