474766-89-7

Upstream product

• 474766-88-6 (13R)-13-deoxy-13-tert-butylperoxy-7-O-(triethylsilyl)baccatin III 
• 155588-14-0 13-deoxybaccatin III 
• 155588-13-9 (2aR,4S,4aS,6R,11S,12S,12aR,12bS)-12-benzoyloxy-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-triethylsilyloxy-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)diyl diacetate 
• 994-30-9 triethylsilyl chloride 

Downstream Products

• 150665-56-8 7-O-triethylsilyl-13-keto baccatin III 

Relevant academic research and scientific papers

Synthetic studies with 13-deoxybaccatin III

An efficient synthesis of 13-epi-7-O-(triethylsilyl)baccatin III from 13-deoxybaccatin III is described. Oxidation of 13-deoxy-7-O-(triethylsilyl)baccatin III with tert-butyl peroxide, followed by reduction with SmI2, produced 13-epi-7-O-(triethylsilyl)baccatin III in good overall yield. The preparation of 13-oxo-7-O-(triethylsilyl)baccatin III from 13-epi-7-O-(triethylsilyl)baccatin III using tetrapropylammonium perruthenate and N-methylmorpholine N-oxide is also reported.