474779-48-1Relevant academic research and scientific papers
Synthesis and effect of substituent position on anti-inflammatory activity of 3-(halobenzyl)isocarbostyrils
Babar, Tariq Mahmood,Naseer, Muhammad Moazzam,Ali, Farukh Iftakhar,Rama, Nasim Hasan,Hadda, Taibi Ben
, p. 4607 - 4618 (2014)
A series of new natural product skeleton based 3-(halobenzyl)isocarbostyrils (2a-2i), were designed and synthesized to examine the effect of position of different halide substituents on anti-inflammatory activity. The structure-activity relationship shows
Isoquinolinone derivatives
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, (2008/06/13)
Derivatives of isoquinolinone and dihydrolisoquinolinone, and related compounds, and their use as pharmaceuticals in the treatment of a disease by inhibition of the enzyme poly(ADP-ribose)polymerase (“PARP”) are disclosed.
