474831-52-2Relevant academic research and scientific papers
Enantioselective Diels-Alder reactions of enals: Fighting species multiplicity of the catalyst with donor solvents
Sartor,Saffrich,Helmchen,Richards,Lambert
, p. 639 - 642 (1991)
Chiral Lewis acids obtained from reactions of N-arylsulphonylamino acids with borane adducts effectively catalyze Diels-Alder additions of α,β-unsaturated aldehydes. Maximum enantioselectivity (methacrylaldehyde: 86 %ee, crotonaldehyde: 81 %ee) was achieved in donor solvents. The first results with new chiral Lewis acids derived from C2-symmetric N-sulphonyl derivatives of 2,2'-diamino-1,1'-binaphthyl are also presented.
