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DSPE-PEG-Amine, with a molecular weight of 2,000, is a PEG polymer that incorporates DSPE and amine end groups. DSPE-PEG-Amine has been approved by the FDA for use in medical applications. The hydrophobic DSPE segment enables encapsulation and aggregation of hydrophobic drugs, while the hydrophilic PEG component enhances the water solubility of the compound, facilitating drug delivery. The amine end group can form a stable amide bond with activated NHS ester, allowing for versatile conjugation options.

474922-26-4

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474922-26-4 Usage

Uses

Used in Pharmaceutical Industry:
DSPE-PEG-Amine is used as a drug delivery carrier for enhancing the solubility and bioavailability of hydrophobic drugs. Its hydrophobic DSPE segment allows for the encapsulation of drugs, while the hydrophilic PEG chain increases the overall water solubility, improving the drug's delivery and therapeutic efficacy.
Used in Bioconjugation:
DSPE-PEG-Amine is used as a bioconjugation agent for attaching various biomolecules, such as peptides, proteins, or antibodies, to drug delivery systems or other surfaces. The amine group can react with activated NHS ester to form a stable amide bond, enabling the covalent attachment of these biomolecules for targeted drug delivery or other applications.
Used in Diagnostic Imaging:
DSPE-PEG-Amine is used as a contrast agent in diagnostic imaging techniques, such as magnetic resonance imaging (MRI) or computed tomography (CT). The PEG polymer can be modified with imaging agents, like gadolinium or iodine, to enhance the visibility of specific tissues or structures within the body, improving diagnostic accuracy.
Used in Cosmetics Industry:
DSPE-PEG-Amine is used as a skin permeation enhancer in transdermal drug delivery systems or cosmetic formulations. The hydrophilic-hydrophobic balance provided by the PEG and DSPE segments allows for improved penetration of active ingredients through the skin, enhancing the effectiveness of topical applications.
Used in Nanotechnology:
DSPE-PEG-Amine is used in the development of nanoparticles for drug delivery, gene therapy, or other biomedical applications. The amphiphilic nature of the polymer allows for the formation of stable nanoparticles with encapsulated drugs or other therapeutic agents, improving their delivery and bioavailability.

Check Digit Verification of cas no

The CAS Registry Mumber 474922-26-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,4,9,2 and 2 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 474922-26:
(8*4)+(7*7)+(6*4)+(5*9)+(4*2)+(3*2)+(2*2)+(1*6)=174
174 % 10 = 4
So 474922-26-4 is a valid CAS Registry Number.

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474922-26-4Downstream Products

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