475-40-1Relevant articles and documents
SINTESIS DE NAFTAZARINAS HIDROXILADAS
Farina, F.,Fernandez, E.,Gimeno, V.,Valderrama, J. A.
, p. 220 - 229 (2007/10/03)
A variety of naphthazarines type 4 and 8 were prepared through Diels-Alder reactions of substituted 1,4-benzoquinones with 1,3-dienes.Thiele-Winter reaction of 5 afforded 6 which by chromic oxidation yielded naphthazarines 7 and/or naphthoquinones 9.Hydroxynaphthazarines of type 8 were synthesized from 5 through 2,3-epoxides of the type 14.The structural study of the products, by 1H-NMR, showed the typical tautomerism of the naphthazarine system.Palabras clave: hidroxinaftazarinas, reaccion Diels-Alder, reaccion Thiele-Winter