475113-76-9

Basic information

• Product Name: (4,5-dimethoxy-2-tritylsulfanyl-benzylamino)-acetic acid methyl ester
• CAS NO: 475113-76-9
• Molecular Weight: 513.657
• Mol File: 475113-76-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4,5-dimethoxy-2-tritylsulfanyl-benzylamino)-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4,5-dimethoxy-2-tritylsulfanyl-benzylamino)-acetic acid methyl ester(475113-76-9)
• EPA Substance Registry System: (4,5-dimethoxy-2-tritylsulfanyl-benzylamino)-acetic acid methyl ester(475113-76-9)

Safety Data

• Hazardous Substances Data: 475113-76-9(Hazardous Substances Data)

Upstream product

• 96-32-2 bromoacetic acid methyl ester 
• 341972-47-2 4,5-dimethoxy-2-(triphenylmethylthio)benzylamine 
• 76-83-5 trityl chloride 

Relevant articles and documents

Synthesis and application of an auxiliary group for chemical ligation at the X-gly site.

An efficient synthesis of an auxiliary group, the 2-mercapto-4,5-dimethoxybenzyl (Dmmb) moiety, to form a Gly-building block is presented. The building block was incorporated into peptides to study the reaction with thiobenzyl-activated derivatives. The target peptides have been obtained by standard chemical ligation reaction, followed by TMSBr-assisted cleavage to remove the auxiliary group. Prior to Dmmb removal, under acidic conditions an unexpected rearrangement was observed and evidence for a mechanism is provided.