475208-64-1

Basic information

• Product Name: 5-nonylbenzaldehyde
• Synonyms: 5-nonylbenzaldehyde
• CAS NO: 475208-64-1
• Molecular Weight: 232.366
• Mol File: 475208-64-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-nonylbenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-nonylbenzaldehyde(475208-64-1)
• EPA Substance Registry System: 5-nonylbenzaldehyde(475208-64-1)

Safety Data

• Hazardous Substances Data: 475208-64-1(Hazardous Substances Data)

Upstream product

• 3452-09-3 1-nonyne 
• 475208-88-9 3-nonyl-benzoic acid ethyl ester 
• 58313-23-8 3-iodobenzoic acid methyl ester 
• 475208-98-1 (3-nonyl-phenyl)-methanol 

Downstream Products

• 252735-69-6 2-hydroxy-3-(morpholinomethyl)-5-nonylbenzaldehyde 

Relevant articles and documents

Development of novel EDG3 antagonists using a 3D database search and their structure-activity relationships

Sphingosine-1-phosphate (S1P) is an intracellular second messenger and an extracellular mediator through endothelial differentiation gene (EDG) receptors, which are a novel class of G-protein-coupled receptors. Although EDG has attracted much attention because of its various roles, no selective agonists or antagonists have yet been developed. This could account for the delay in clarifying the physiological roles of members of the EDG family. Because precise structural information on EDG receptors is not yet available, pharmacophore models were generated based on structural information for S1P using the rational drug design software Catalyst. Novel antagonists, 2-alkylthiazolidine-4-carboxylic acids, were retrieved from a three-dimensional database search using the pharmacophore models, and these showed activity for EDG3. On the basis of their nonphosphoric acid structure, more potent antagonists, 2-(m- or p-heptylphenyl)thiazolidine-4-carboxylic acid, were developed.