475232-11-2

Upstream product

• 474745-86-3 (2S,4R,4'S,6'R)-1-[6'-benzyloxymethyl-4'-(4-methoxy-benzyloxy)-5',6'-dihydro-4'H-pyran-2'-yl]-6-(4-methoxy-benzyloxy)-hexane-2,4-diol 
• 3396-11-0 cesium acetate 

Downstream Products

• 475232-12-3 (2S,4R,6R,8R,10S,11R)-8-benzyloxymethyl-11-iodo-10-(4-methoxy-benzyloxy)-2-[2-(4-methoxybenzyl)ethyl]-1,7-dioxa-spiro[5.5]undecan-4-ol 
• 475232-08-7 (2S,6S,8R,10S)-8-benzyloxymethyl-10-(4-methoxy-benzyloxy)-2-[2-(4-methoxy-benzyloxy)-ethyl]-1,7-dioxa-spiro[5.5]undecan-4-one 
• 475232-09-8 (2S,4R,6R,8R,10S)-8-benzyloxymethyl-10-(4-methoxy-benzyloxy)-2-[2-(4-methoxy-benzyloxy)-ethyl]-1,7-dioxa-spiro[5.5]undecan-4-ol 
• 475232-10-1 (2R,4S,4'S,6'R)-1-[6'-benzyloxymethyl-4'-(4-methoxy-benzyloxy)-5',6'-dihydro-4'H-pyran-2'-yl]-6-(4-methoxy-benzyloxy)-hexane-2,4-diol 

Relevant academic research and scientific papers

Synthesis of the C(2)-C(13) fragment (the A-B spiroketal unit) of spongistatin 1 (altohyrtin A): use of a common intermediate for the synthesis of both spongistatin spiroketals.

[reaction: see text] A convergent synthesis of 14 corresponding to the A-B spiroketal core of spongistatin 1 has been accomplished via an iodo-spiroketalization reaction of glycal 9, which was synthesized in three steps from a late-stage intermediate used