475489-94-2

Upstream product

• 6393-40-4 4-Amino 3-nitro-benzonitrile 
• 17626-40-3 4-cyano-1,2-phenylenediamine 
• 874-42-0 2,4-dichlorobenzaldeyhde 

Downstream Products

• 1269439-91-9 5-formyl-2-(2,4-dichlorophenyl)benzimidazole 
• 1269439-94-2 2-(2,4-dichlorophenyl)-5-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazole 

Relevant academic research and scientific papers

Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-Aryl-substituted 2-bis-1H-benzimidazoles

Inhibitors of topoisomerase I constitute a novel family of antitumor agents. The class of benzimidazole derivatives contains compounds possessing affinity to DNA. For example, fluorescent stains Hoechst 33342 and Hoechst 33258 interact with DNA as ligand

Synthesis of some new 2-substituted-phenyl-1H-benzimidazole-5-carbonitriles and their potent activity against Candida species

New 2-substituted-phenyl-1H-benzimidazole-5-carboxylic acids (35, 38), ethyl-5-carboxylate (36), -5-carboxamides (37, 39),-5-carboxaldehyde (42), -5-chloro (40), -5-trifluoromethyl (41), and -5-carbonitriles (44-53, 55-67), -6-carbonitrile (54) were prepa