475579-35-2

Upstream product

• 179128-57-5 (24R)-3β-acetoxy-24-benzoyloxycholesta-5,25-diene 
• 179128-56-4 (24R)-3β-acetoxy-24-benzoyloxy-25-hydroxycholest-5-ene 
• 475579-31-8 (24R)-3β-acetoxy-24-benzoyloxycholest-5-en-7-one 
• 179128-58-6 (24R)-3β-acetoxy-24-benzoyloxycholest-5-ene 
• 64727-04-4 Δ⁵-3β,24(R),25-trihydroxycholestene-3-acetate 
• 2665-04-5 demosterol acetate 
• 313-04-2 demosterol 
• 475579-33-0 (5α,24R)-3β-acetoxy-24-benzoyloxy-7-β-hydroxycholestane 

Downstream Products

• 635302-51-1 (5α,24R)-24-benzoyloxy-3β-hydroxycholestan-7-one 
• 301695-61-4 (5α,7α,24R)-7,24-dihydroxy-3-ketocholestane 
• 475579-41-0 (5α,24R)-24-benzoyloxy-7α-hydroxycholestan-3-one 
• 475579-39-6 (5α,24R)-24-benzoyloxy-3β,7α-dihydroxycholestane 

Relevant academic research and scientific papers

Formal synthesis of squalamine from desmosterol

The key intermediate to squalamine, (5α, 7α, 24R)-7,24-dihydroxy-cholestan-3-one, was synthesized from the 3-O-acetyl-24R,25-dihydroxy derivative of desmosterol via 10 steps in 16% overall yield and squalamine was also prepared via two further steps in 7.