475682-46-3

Upstream product

• 475682-45-2 [(2S)-8-methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl]methanol 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 475682-44-1 [(2R)-8-methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl]methanol 
• 5683-33-0 2-(Dimethylamino)pyridine 

Downstream Products

• 675877-15-3 S-4-benzo[b]thiophen-7-yl-1-(8-methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-ylmethyl)-pyridinium 4-bromobenzenesulfonate 
• 460353-65-5 SSA-426 

Relevant academic research and scientific papers

ANTIDEPRESSANT ARYLPIPERAZINE DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS

Compounds of the formula I: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive-compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.

ANTIDEPRESSANT PIPERIDINE DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS

Compounds of the Formula: are useful for the treatment of depression (including but not limited to major depressive disorder, chi ldhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (a

ANTIDEPRESSANT AZAHETEROCYCLYLMETHYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS

Compounds of the Formula: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as premenstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.

ANTIDEPRESSANT INDOLEALKYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXAN METHYLAMINES

Compounds of the Formula: are useful for the treatment of depression ( including but not limited to major depressive disorder, childhood depression and dysthymia). Anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (a

Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline

Methods of preparing compounds of Formula I are provided.