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Phenoxymethylpenicillin 3-aldehyde, also known as penicillin G aldehyde, is a key intermediate in the synthesis of various semi-synthetic penicillins. It is derived from the chemical modification of penicillin G, where the side chain is removed to expose the aldehyde group. This aldehyde group allows for further chemical reactions to attach different side chains, resulting in the creation of new penicillin derivatives with specific antibiotic properties. Phenoxymethylpenicillin 3-aldehyde is crucial in the pharmaceutical industry for the development of customized antibiotics to combat various bacterial infections.

4759-86-8

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4759-86-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4759-86-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,5 and 9 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4759-86:
(6*4)+(5*7)+(4*5)+(3*9)+(2*8)+(1*6)=128
128 % 10 = 8
So 4759-86-8 is a valid CAS Registry Number.

4759-86-8Downstream Products

4759-86-8Relevant academic research and scientific papers

Penicillin 3-aldehyde is a good substrate and not an inhibitor of β-lactamases A and C

Layland, Nicola J.,Laws, Andrew P.,Vilanova, Bartolome,Page, Michael I.

, p. 869 - 870 (2007/10/02)

Replacement of the 3-carboxylate residue in phenoxymethylpenicillin by an aldehyde group gives a good substrate for E,cloacae P99 β-lactamase with kcat = 34 s-1, Km = 7.5x10-5 mol dm-3 and kcat/

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