475977-62-9Relevant articles and documents
Synthesis of new analogs of the C-13 docetaxel side chain by asymmetric aminohydroxylation
Montiel-Smith, Sara,Cervantes-Mejia, Vicente,Dubois, Joelle,Guenard, Daniel,Gueritte, Francoise,Sandoval-Ramirez, Jesus
, p. 2260 - 2264 (2002)
The synthesis of six new β-phenyl isoserines, each bearing an amino or a nitro substituent on the phenyl ring in various positions, is reported. These compounds, analogues of the docetaxel side chain, have been obtained by asymmetric aminohydroxylation of the corresponding cinnamates with excellent regiospecificity and in good enantiomeric excess. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.