475977-79-8 Usage
Description
2-(2,4-Dinitrobenzylthio)-1H-benzo[d]imidazole is a chemical compound with the molecular formula C14H10N4O4S. It is a benzimidazole derivative featuring a dinitrobenzene group and a thiol group attached to it. 2-(2,4-DINITROBENZYLTHIO)-1H-BENZO[D]IMIDAZOLE has been studied for its potential applications in various fields, including its use as a fluorescent label for protein imaging, a photosensitizer for photodynamic therapy, and for its biological activities such as anti-tumor and anti-inflammatory properties. Its unique structure and potential applications make it of interest in medicine and biochemistry, with ongoing research to further explore its uses and effects.
Uses
Used in Biomedical Research:
2-(2,4-Dinitrobenzylthio)-1H-benzo[d]imidazole is used as a fluorescent label for protein imaging, allowing researchers to track and visualize the behavior of proteins within biological systems.
Used in Photodynamic Therapy:
2-(2,4-DINITROBENZYLTHIO)-1H-BENZO[D]IMIDAZOLE serves as a photosensitizer, which, when activated by light, can generate reactive oxygen species to target and destroy cancer cells, making it a potential candidate for the treatment of various types of cancer.
Used in Drug Development:
2-(2,4-Dinitrobenzylthio)-1H-benzo[d]imidazole is used in the development of new drugs due to its biological activities, such as its anti-tumor and anti-inflammatory properties, which may contribute to the creation of novel therapeutic agents for various diseases.
Used in Chemical Synthesis:
In the chemical industry, 2-(2,4-Dinitrobenzylthio)-1H-benzo[d]imidazole may be used as an intermediate in the synthesis of other complex organic compounds, leveraging its unique structure and reactivity.
Used in Analytical Chemistry:
2-(2,4-DINITROBENZYLTHIO)-1H-BENZO[D]IMIDAZOLE can be employed as a reagent or a reference standard in analytical chemistry for the development of new methods or the calibration of instruments, given its distinct chemical and physical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 475977-79-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,9,7 and 7 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 475977-79:
(8*4)+(7*7)+(6*5)+(5*9)+(4*7)+(3*7)+(2*7)+(1*9)=228
228 % 10 = 8
So 475977-79-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H10N4O4S/c19-17(20)10-6-5-9(13(7-10)18(21)22)8-23-14-15-11-3-1-2-4-12(11)16-14/h1-7H,8H2,(H,15,16)
475977-79-8Relevant articles and documents
Synthesis and preliminary evaluation of benzimidazole derivatives as antimicrobial agents
Klimesova, Vera,Koci, Jan,Pour, Milan,Stachel, Jiri,Waisser, Karel,Kaustova, Jarmila
, p. 409 - 418 (2007/10/03)
A series of 2-alkylsulphanylbenzimidazoles was synthesised and the compounds were evaluated for their in vitro antimicrobial activity. The structures of the compounds were confirmed by 1H-NMR and IR data, and their purity by elemental analysis. Antimycobacterial activities against Mycobacterium tuberculosis and non-tuberculous mycobacteria as well as antifungal activities against Candida albicans, Candida tropicalis, Candida krusei, Candida glabrata, Trichosporon beigelii, Trichophyton mentagrophytes and Aspergillus fumigatus were expressed as the corresponding MIC values. The substances exhibited appreciable antimycobacterial activity, in particular, against non-tuberculous mycobacteria. The activity of the most active compound in the set, 3,5-dinitro derivative 4t, exceeded that of the standard isoniazide against M. kansasii and M. avium. The antifungal activities of the compounds were relatively low. A weak antifungal effect was observed against the dermatophyte Trichophyton mentagrophytes. None of the compounds showed significant inhibitory activity against yeasts.
