475985-08-1

Upstream product

• 19005-93-7 1H-indol-2-ylcarboxaldehyde 
• 1521-51-3 rac-3-bromocyclohexene 
• 3770-50-1 2-carbethoxyindole 
• 475985-07-0 N-(cyclohex-2-enyl)-2-(hydroxymethyl)indole 
• 475985-06-9 1-cyclohex-2-enyl-1H-indole-2-carboxylic acid ethyl ester 

Downstream Products

• 475985-10-5 (+)-(αR,2aR,5aS,11bR,11cR)-1-(α-methylbenzyl)-1,2a,3,4,5,5a,11b,11c-octahydroindolo[1,2-a]isoxazolo[3,4,5-c,d]indole 
• 475985-11-6 (-)-(αR,2aS,5aR,11bS,11cS)-1-(α-methylbenzyl)-1,2a,3,4,5,5a,11b,11c-octahydroindolo[1,2-a]isoxazolo[3,4,5-c,d]indole 

Relevant academic research and scientific papers

Building polycyclic indole scaffolds via gold(I)-catalyzed intra- and inter-molecular cyclization reactions of 1,6-enynes

A gold(I) catalyzed cycloisomerization of indolyl-1,6-enynes via 5-exo-dig cyclization is reported. The reaction passes through an intermediate whose fate can be steered to yield different indole polycyclic scaffolds through various intra- and inter-molecular cyclization reactions. One of the key transformations of indolyl-1,6-enynes was a formal [2+2+2] cycloaddition reaction with various aldehydes to afford natural product-like tetracyclic indoles.

A valuable approach to enantiopure partially saturated pyrrolo- and indolo[1,2-a]indoles by intramolecular nitrone cycloadditions to the cyclohexene ring

Enantiopure representatives of the title heterocyclic systems, which are of interest in alkaloid chemistry, are accessible by a procedure based upon intramolecular cycloadditions of nitrones derived from N-(cyclohex-2-enyl)-substituted pyrrole-2- and indo