476014-79-6Relevant academic research and scientific papers
A stereodivergent approach to substituted 4-hydroxypiperidines
Vink, Mandy K. S.,Schortinghuis, Christien A.,Luten, Jordy,Van Maarseveen, Jan H.,Schoemaker, Hans E.,Hiemstra, Henk,Rutjes, Floris P. J. T.
, p. 7869 - 7871 (2007/10/03)
A stereodivergent route toward both diastereomeric forms of functionalized 4-hydroxypiperidines has been successfully developed. This route involves biocatalytic generation of the enantiopure starting materials followed by functionalization via N-acyliminium ion-mediated CC-bond formation.
