476014-92-3

Usage

Uses

Used in Pharmaceutical Industry:
4-(S)-HYDROXY-2-PIPERIDINONE is used as a key intermediate for the synthesis of drugs with a broad spectrum of biological activities, contributing to the development of new medications with potential therapeutic benefits.
Used in Agrochemical Synthesis:
In the agrochemical sector, 4-(S)-HYDROXY-2-PIPERIDINONE is utilized as an essential component in the creation of various agrochemicals, enhancing crop protection and management strategies.
Used in Vitamin Production:
4-(S)-HYDROXY-2-PIPERIDINONE is employed in the production of vitamins, playing a critical role in ensuring the nutritional quality of these essential compounds.
Used as a Chelating Agent:
4-(S)-HYDROXY-2-PIPERIDINONE is used as a chelating agent for metal ions, which can be beneficial in various applications, including environmental remediation and the stabilization of metal ions in biological systems.
Used in Antioxidant Research:
4-(S)-HYDROXY-2-PIPERIDINONE is studied for its potential as an antioxidant, which could have implications for health and disease prevention by combating oxidative stress in biological systems.
Used in the Synthesis of Natural Products and Heterocyclic Compounds:
4-(S)-HYDROXY-2-PIPERIDINONE is used as a key building block in the synthesis of natural products and functionalized heterocyclic compounds, which are important in various chemical and pharmaceutical applications.

Upstream product

• 158849-52-6 4-cyano-3-hydroxybutyric acid methyl ester 
• 50607-30-2 piperidine-2,4-dione 
• 141942-85-0 (R)-ethyl 4-cyano-3-hydroxybutyrate 
• 147028-51-1 4-cyano-3-hydroxybutanoic acid 

Downstream Products

• 50607-30-2 piperidine-2,4-dione 
• 476014-80-9 4-hydroxy-6-methoxypiperidin-2-one 
• 476014-80-9 4-hydroxy-6-methoxypiperidin-2-one 

Relevant academic research and scientific papers

OXAZOLIDONE COMPOUND, PREPARING METHOD AND APPLICATION THEREOF

The present invention relates to the field of a pharmaceutical compound, and more specifically, relates to a new oxazolidone compound, an enantiomer, a diastereoisomer and a raceme thereof, and a mixture thereof, and a pharmaceutically acceptable salt thereof, a preparation method thereof, an application thereof as a bioactive substance in a drug. The compound in the present invention has strong anticoagulant activity, does not affect the activity of thrombin, and can reduce the risk of hemorrhage. A pharmacokinetics experiment shows that the compound in the present invention further has good metabolic characteristics, and has a far better oral bioavailability than a positive contrastive agent rivaroxaban.

SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF USE

The present invention provides novel substituted cyclic compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.

Synthesis of both enantiomers of the Streptomyces alkaloid 4-epi-SS20846A

The enantiodivergent synthesis of the Streptomyces alkaloid 4-epi-SS20846A was based on a Takai olefination/Suzuki-Miyaura coupling sequence for the highly stereoselective introduction of the E,E-pentadienyl side chain on the piperidine skeleton. Optical

A stereodivergent approach to substituted 4-hydroxypiperidines

A stereodivergent route toward both diastereomeric forms of functionalized 4-hydroxypiperidines has been successfully developed. This route involves biocatalytic generation of the enantiopure starting materials followed by functionalization via N-acyliminium ion-mediated CC-bond formation.