4761-00-6Relevant articles and documents
Synthesis, molecular docking, and in silico ADMET studies of 4-benzyl-1-(2,4,6-trimethyl-benzyl)-piperidine: Potential Inhibitor of SARS-CoV2
Nandini Asha,Ravindran Durai Nayagam,Bhuvanesh, Nattamai
, (2021)
Nowadays, over 200 countries face a wellbeing emergency because of epidemiological disease COVID-19 caused by the SARS-CoV-2 virus. It will cause a very high effect on the world's economy and the worldwide health sector. The present work is an investigati
Synthesis of new bipyridine N,N′-dioxides and their application in asymmetric allylation of benzaldehyde and aldol addition to acetophenone
Bedná?ová, Eva,Ne?as, David,Císa?ová, Ivana,Du?ek, Michal,Lamaty, Frédéric,Kotora, Martin
, p. 29 - 48 (2018/11/23)
Abstract: Two methods for the synthesis of new axially chiral bipyridine N,N′-dioxides based on catalytic [2+2+2] cyclotrimerization of diynes with nitriles were developed. The N,N′-dioxides were used as catalysts in enantioselective allylation of benzaldehyde with allyltrichlorosilane and aldol reaction of trichlorosilyl ketene acetal of methyl acetate with acetophenone. Graphical abstract: [Figure not available: see fulltext.].
Application of novel multi-cationic ionic liquids in microwave assisted 2-amino-4H-chromene synthesis
Kumbhar, Arjun,Jadhav, Sanjay,Shejwal, Rajendra,Rashinkar, Gajanan,Salunkhe, Rajshri
, p. 19612 - 19619 (2016/03/01)
Novel multi-cationic ionic liquids containing a mesitylene backbone with acetate and methane sulphonate anions have been synthesized. These ionic liquids were used for the synthesis of 2-amino-4H-chromenes under microwave heating. The effects of nature and amount of ionic liquids on the yield and reaction time were thoroughly investigated. The ionic liquids showed a considerable level of reusability without a significant decrease in catalytic activity. We have successfully combined the advantages of microwave technology with ionic liquids to facilitate the rapid construction of chromene skeletons from readily obtainable and inexpensive materials via a multicomponent strategy.