476153-60-3Relevant academic research and scientific papers
Regiospecific synthesis of a bridgehead-functionalized bicyclo[2.2.2]octenone
Kende, Andrew S.,Lan, Jiong,Arad, Dorit
, p. 5237 - 5239 (2002)
Three independent strategies are tested toward the synthesis of the protected 1-aminobicyclo[2.2.2]octene ketodiester 1. One of these three is found to be completely regioselective. It proceeds by Diels-Alder addition of dimethyl acetylenedicarboxylate to
