476186-34-2Relevant academic research and scientific papers
MMP-13 selective α-sulfone hydroxamates: A survey of P1′ heterocyclic amide isosteres
Barta, Thomas E.,Becker, Daniel P.,Bedell, Louis J.,Easton, Alan M.,Hockerman, Susan L.,Kiefer, James,Munie, Grace E.,Mathis, Karl J.,Li, Madeleine H.,Rico, Joseph G.,Villamil, Clara I.,Williams, Jennifer M.
scheme or table, p. 2820 - 2822 (2011/06/26)
Seeking compounds preferentially potent and selective for MMP-13, we reported in the preceding Letter on a series of hydroxamic acids with a flexible benzamide tail groups.1a Here, we replace the amide moiety with non-hydrolyzable heterocycles
