476276-80-9Relevant articles and documents
Palladium-catalyzed oxidative C-H bond acylation of acetanilides with benzylic alcohols
Yuan, Yu,Chen, Duanteng,Wang, Xiaowei
, p. 3373 - 3379 (2012/02/03)
An efficient and clean method to construct C-C bonds has been developed via the acylation reaction of acetanilides with benzylic alcohols using tert-butyl hydroperoxide (TBHP) as oxidant catalyzed by palladium acetate in the presence of triflic acid (TfOH). The acylation reactions exhibit excellent reactivities, and up to 95% yield of the corresponding aryl ketone could be obtained under the optimal conditions. Copyright