476331-49-4Relevant academic research and scientific papers
Synthesis of termini-differentiated 6-carbon stereotetrads: An alkylative oxidation strategy for preparation of the C21-C26 segment of apoptolidin
Chen, Yuzhong,Evarts Jr., Jerry B.,Torres, Eduardo,Fuchs, Philip L.
, p. 3571 - 3574 (2002)
(graph presented) Two methods have been developed for the synthesis of epoxide 36. The first uses (+)-pulegone 25 as an enantiopure starting material and introduces the requisite intricacy of target 22 in 12 operations. The second method employs an enanti
Jacobsen protocols for large-scale epoxidation of cyclic dienyl sulfones: Application to the (+)-pretazettine core
Ebrahimian, G. Reza,Du Jourdin, Xavier Mollat,Fuchs, Philip L.
supporting information; experimental part, p. 2630 - 2633 (2012/07/17)
A Jacobsen epoxidation protocol using H2O2 as oxidant was designed for the large-scale preparation of various epoxy vinyl sulfones. A number of cocatalysts were screened, and pH control led to increased reaction rate, higher turnover
