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(R)-BorohomoPhe-(+)-Pinanediol-HCl is a chiral reagent that features a boron atom attached to a homo-phenyl group and a pinanediol moiety, existing as a hydrochloride salt. (R)-BorohomoPhe-(+)-Pinanediol-HCl is renowned for its utility in organic synthesis, particularly as a chiral auxiliary for the enantioselective reduction of ketones and imines. The presence of the boron atom facilitates the manipulation of stereochemistry within the target molecule, while the pinanediol group enhances stereoselectivity. This reagent has established itself as a versatile and efficient tool in asymmetric synthesis, with applications extending to the creation of pharmaceuticals, agrochemicals, and fine chemicals.

476334-33-5

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476334-33-5 Usage

Uses

Used in Pharmaceutical Synthesis:
(R)-BorohomoPhe-(+)-Pinanediol-HCl is utilized as a chiral auxiliary for the enantioselective reduction of ketones and imines, which is crucial in the production of pharmaceuticals. Its ability to influence the stereochemistry of target molecules ensures the creation of enantiomerically pure compounds, a critical factor in drug efficacy and safety.
Used in Agrochemical Synthesis:
In the agrochemical industry, (R)-BorohomoPhe-(+)-Pinanediol-HCl serves as a chiral auxiliary, aiding in the enantioselective synthesis of active ingredients for pesticides and herbicides. The precise control over stereochemistry provided by this reagent is essential for developing agrochemicals with targeted effects on pests and weeds, minimizing impact on non-target organisms and the environment.
Used in Fine Chemicals Synthesis:
(R)-BorohomoPhe-(+)-Pinanediol-HCl is employed as a chiral auxiliary in the synthesis of fine chemicals, which are high-purity chemicals used in various applications such as fragrances, flavors, dyes, and high-value specialty chemicals. The reagent's capacity to guide the stereoselective reduction of ketones and imines contributes to the production of enantiomerically pure fine chemicals, which is vital for their performance and quality.
Overall, (R)-BorohomoPhe-(+)-Pinanediol-HCl is a valuable asset in the fields of pharmaceuticals, agrochemicals, and fine chemicals, providing a reliable means to achieve the desired stereochemistry in a wide range of chemical syntheses.

Check Digit Verification of cas no

The CAS Registry Mumber 476334-33-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,6,3,3 and 4 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 476334-33:
(8*4)+(7*7)+(6*6)+(5*3)+(4*3)+(3*4)+(2*3)+(1*3)=165
165 % 10 = 5
So 476334-33-5 is a valid CAS Registry Number.

476334-33-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-BorohomoPhe-(+)-Pinanediol-hydrochloride

1.2 Other means of identification

Product number -
Other names (R)-BorohomoPhe-(+)-Pinanediol-HCl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:476334-33-5 SDS

476334-33-5Downstream Products

476334-33-5Relevant academic research and scientific papers

P1 Phenethyl peptide boronic acid inhibitors of HCV NS3 protease

Priestley,De Lucca, Indawati,Ghavimi, Bahman,Erickson-Viitanen, Susan,Decicco, Carl P.

, p. 3199 - 3202 (2007/10/03)

A series of peptide boronic acids containing extended, hydrophobic P1 residues was prepared to probe the shallow, hydrophobic S1 region of HCV NS3 protease. The p-trifluoromethylphenethyl P1 substituent was identified as optimal with respect to inhibitor potency for NS3 and selectivity against elastase and chymotrypsin.

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