476468-29-8Relevant academic research and scientific papers
Synthesis of 2,6-dideoxysugars via ring-closing olefinic metathesis.
Andreana, Peter R,McLellan, Jason S,Chen, Yongchen,Wang, Peng George
, p. 3875 - 3878 (2007/10/03)
[formula: see text] Grubbs' RuCl2 (=CHPh)(PCy3)2 (catalyst 1) and RuCl2(=CHPh)(PCy3)(IMess) (catalyst 2) complexes have been successfully utilized in the construction of beta,gamma-unsaturated delta-lactones containing various substitution patterns of methyl groups. Asymmetric dihydroxylation followed by reduction leads to 3,4-cis-dihydroxy-2,6-dideoxypyranoses, which have proven to play very important biological roles as key components of natural products.
