476468-83-4

Basic information

• Product Name: methyl 2-methyl-2-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)propanoate
• Synonyms: methyl 2-methyl-2-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)propanoate
• CAS NO: 476468-83-4
• Molecular Weight: 326.293
• Mol File: 476468-83-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 2-methyl-2-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-methyl-2-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)propanoate(476468-83-4)
• EPA Substance Registry System: methyl 2-methyl-2-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)propanoate(476468-83-4)

Safety Data

• Hazardous Substances Data: 476468-83-4(Hazardous Substances Data)

Upstream product

• 547-63-7 Methyl isobutyrate 
• 66107-30-0 4-bromophenyl trifluoromethanesulfonate 
• 109586-39-2 4-iodophenyl trifluoromethanesulfonate 
• 859828-48-1 methyl 2-{4-(trifluoromethanesulfonyloxy)phenyl}propanoate 
• 74-88-4 methyl iodide 

Downstream Products

• 865186-96-5 2-methyl-2-(4-{[(trifluoromethyl)sulfonyl]oxy}phenyl)propanoic acid 

Relevant articles and documents

α-Arylation of Esters and Ketones Enabled by a Bench-Stable Pd(I) Dimer Catalyst

A procedure for the α-arylation of α,α-disubstituted esters and ketones to generate quaternary carbon centers is described. The developed protocol is operationally simple and employs an air- and moisture-stable dinuclear Pd(I) complex [Pd(μ-I)(P t -Bu 3)] 2 to mediate selective α-arylation of aromatic C-I/Br bonds in the presence of aromatic C-Cl and/or C-OTf sites.

2-aryl-propionamide derivatives useful as bradykinin receptor antagonists and pharmaceutical compositions containing them

(R,S) 2-aryl-propionamide derivatives, or their single enantiomers (R) and (S) are disclosed useful in the treatment or prevention of symptoms and disorders such as pain and inflammation associated with the bradykinin B1 pathway.