476478-37-2Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of new methyloxiranylmethoxyxanthone analogues
Woo, Sangwook,Kang, Da-Hye,Nam, Jung Min,Lee, Chong Soon,Ha, Eun-Mi,Lee, Eung-Seok,Kwon, Youngjoo,Na, Younghwa
experimental part, p. 4221 - 4228 (2010/09/16)
In order to develop potential anti-cancer agents that act on topoisomerase II and DNA, we have synthesized 12 new xanthone derivatives. In the cytotoxicity test, compounds 17 and 31 exhibited 2- to 7-fold stronger inhibitory activity than adriamycin again
Methods for preparation and use of psorospermin analogs
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, (2008/06/13)
Psorospermin is a cytotoxic dihydroflranoxanthone that has found to exhibit significant activity against various tumor cell lines. Unfortunately, psorospermin is no longer readily available from its natural plant source. The present invention is directed
