47689-67-8

Basic information

• Product Name: Boc-O-(2-bromo-Cbz)-L-Tyrosine
• Synonyms: n-[(1,1-dimethylethoxy)carbonyl]-l-tyrosin(2-bromophenyl)methylcarbonate;BOC-(2-BROMO-Z)-L-TYROSINE;BOC-L-TYR(BR-Z);BOC-L-TYR(2-BR-Z)-OH;BOC-L-TYROSINE(2-BROMOCBZ);BOC-O-(2-BROMO-Z)-L-TYROSINE;BOC-O-(2-BROMOBENZYLOXYCARBONYL)-L-TYROSINE;BOC-O-(2-BROMO-CBZ)-L-TYROSINE
• CAS NO: 47689-67-8
• Molecular Formula: C₂₂H₂₄BrNO₇
• Molecular Weight: 494.33
• Product Categories: Amino Acid Derivatives;Amino Acids;Boc-Amino Acids and Derivative;Boc-Amino acid series
• Mol File: 47689-67-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 112-115 °C
• Boiling Point: 634.9 °C at 760 mmHg
• Flash Point: 337.8 °C
• Appearance: /
• Density: 1.414 g/cm³
• Vapor Pressure: 5.41E-17mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Boc-O-(2-bromo-Cbz)-L-Tyrosine(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-O-(2-bromo-Cbz)-L-Tyrosine(47689-67-8)
• EPA Substance Registry System: Boc-O-(2-bromo-Cbz)-L-Tyrosine(47689-67-8)

Safety Data

• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 47689-67-8(Hazardous Substances Data)

Usage

Uses

Boc-O-(2-bromo-Z)-L-Tyrosine, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

InChI:InChI=1/C22H24BrNO7/c1-22(2,3)31-20(27)24-18(19(25)26)12-14-8-10-16(11-9-14)30-21(28)29-13-15-6-4-5-7-17(15)23/h4-11,18H,12-13H2,1-3H3,(H,24,27)(H,25,26)/t18-/m0/s1

Downstream Products

• 1022150-46-4 C₅₄H₇₄N₁₆O₉ 
• 1022150-45-3 C₅₄H₇₄N₁₄O₉ 
• 1022150-42-0 C₅₄H₇₄N₁₄O₉ 
• 1022150-38-4 C₅₄H₇₄N₁₆O₉ 
• 1022150-43-1 C₅₄H₇₄N₁₆O₉ 
• 61617-51-4 cyclo(3-14)H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Tyr-Lys-Thr-Phe-Thr-Ser-Cys-OH 
• 1346110-56-2 Tyr-c(D-Lys-Phe-D-Pro-Asp)-NH₂ 
• 1214740-33-6 Tyr-c[D-Lys-Phe-Phe-Asp]NH₂ 
• 1346110-58-4 Tyr-c(D-Asp-Phe-D-Pro-Lys)-NH₂ 
• 145790-78-9 H_.Val_.Gln_.Ala_.Ala_.Ile_.Asp_.Tyr_.Ile_.Asn_.Gly_.OH 
• 120866-05-9 (R)-2-{(S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-(3-nitro-pyridin-2-yldisulfanyl)-propionic acid 
• 120866-06-0 (R)-2-[(S)-2-(2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid [(R)-1-carbamoyl-2-(3-nitro-pyridin-2-yldisulfanyl)-ethyl]-amide 
• 120866-04-8 (R)-2-[(S)-2-(2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-3-(3-nitro-pyridin-2-yldisulfanyl)-propionic acid 
• 138228-38-3 Tyr-D-Arg-Phe-β-Ala-NH2 

Relevant articles and documents

Stable polypeptides having c-AMP production enhancing activity and the use thereof

Disclosed are (1) a polypeptide represented by formula (I), or a pharmaceutically acceptable amide, ester or salt thereof: wherein X is hydrogen atom; or a lower alkyl group which may be substituted with a member selected from the group consisting of hydroxy group, substituted or unsubstituted amino group, carboxyl group, carbamoyl group, and substituted or unsubstituted aromatic group; and Y is one of amino acids or peptides consisting of 1 to 16 amino acid residues counted from the N-terminal side of Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys SEQ ID NO: 20, and (2) a pharmaceutical composition comprising a polypeptide represented by formula (I), or a pharmaceutically acceptable amide, ester or salt thereof, which has remarkable c-AMP activity and is useful as a nerve activating agent.