477197-54-9

Basic information

• Product Name: 3-hydroxy-4,5-bis-(12-hydroxy-dodecyloxy)-benzoic acid methyl ester
• Synonyms: 3-hydroxy-4,5-bis-(12-hydroxy-dodecyloxy)-benzoic acid methyl ester
• CAS NO: 477197-54-9
• Molecular Weight: 552.792
• Mol File: 477197-54-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-4,5-bis-(12-hydroxy-dodecyloxy)-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-4,5-bis-(12-hydroxy-dodecyloxy)-benzoic acid methyl ester(477197-54-9)
• EPA Substance Registry System: 3-hydroxy-4,5-bis-(12-hydroxy-dodecyloxy)-benzoic acid methyl ester(477197-54-9)

Safety Data

• Hazardous Substances Data: 477197-54-9(Hazardous Substances Data)

Upstream product

• 3344-77-2 12-bromododecanol 
• 99-24-1 methyl galloate 

Downstream Products

• 477197-78-7 C₅₅H₉₀O₁₀ 
• 477197-76-5 3-dodecyloxy-4,5-bis-(12-hydroxy-dodecyloxy)-benzoic acid 
• 477197-64-1 3-dodecyloxy-4,5-bis-(12-hydroxy-dodecyloxy)-benzoic acid methyl ester 

Relevant articles and documents

A facile route to multi-functionalization of methyl gallate: Pivotal synthons for mesomorphic materials

The preparation of mono-, di- and trisubstituted gallic derivatives is described using either 1-bromododecane or 12-bromo-1-dodecanol. After saponification of the methyl ester bearing the dodecanol groups, subsequent functionalization with methacryloyl chloride provides the hybrid methacrylate esters/anhydride species. Selective cleavage of the anhydride function gives rise to the corresponding acids, which have been further functionalized to the imine derivative 15 by condensation with 4-[imino-4-(toluyl)]phenol. This reaction is made possible using the acidic form of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide (EDC·HCl) and dimethylaminopyridine (DMAP). Selective hydrolysis of the imine function with a HCl-treated silica provides the targeted aniline in excellent yield.