47727-93-5Relevant articles and documents
Synthesis and biological evaluation of 1,6-bis-triazole-2,3,4-tri-O-benzyl-α-D-glucopyranosides as a novel α-glucosidase inhibitor in the treatment of Type 2 diabetes
Athipornchai, Anan,Chaidam, Suksamran,Saeeng, Rungnapha,Saehlim, Natthiya,Sirion, Uthaiwan
supporting information, (2021/08/27)
A novel series of 1,6-bis-triazole-benzyl-α-glucoside derivatives (7a-7ee) were designed, synthesized and evaluated for inhibitory activity against α-glucosidase. Most of the synthesized compounds exhibited good activity with IC50 ranging from
SGLT-2 INHIBITORS
-
, (2016/04/09)
Provided are compounds of SGLT-2 inhibitors, pharmaceutically acceptable salts, hydrides and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with
Synthesis of the dimethyl ester of 1-deoxy-L-idonojirimycin-1- methylenphosphonate: A new approach to iminosugar phosphonates
La Ferla, Barbara,Bugada, Piergiuliano,Nicotra, Francesco
, p. 151 - 162 (2007/10/03)
1-Methylenphosphonate-1-deoxy-L-idonojirimycin (1) has been synthesized starting from commercially available tetrabenzyl glucose, the key steps being substitution of the hydroxyl group at C-5 of compound 7 with an azido group, stereoselective reaction of