477283-61-7Relevant academic research and scientific papers
Synthesis and characterization of N1-(4-toluenesulfonyl)-N1-(9-anthracenemethyl)triamines
Wang, Chaojie,Abboud, Khalil A.,Phanstiel IV, Otto
, p. 7865 - 7868 (2002)
A modular synthetic approach was developed to access triamines with varying tether lengths from commercially available aminoalkanols. Initial N-alkylation via reductive amination with anthracene-9-carbaldehyde provided the secondary amines in good yield. Subsequent ditosylation with excess TsC1 yielded the respective bis-N,O-tosylates. The tosylates were reacted with excess putrescine to give the final triamines. X-ray crystallography revealed that the polyamine tail is preferentially oriented over the shielding cone of the anthracene ring.
