477289-47-7Relevant academic research and scientific papers
Oxidative spirocyclization of phenolic sulfonamides: Scope and applications
Liang, Huan,Ciufolini, Marco A.
supporting information; experimental part, p. 13262 - 13270 (2011/03/17)
A full account of the oxidative dearomatization of para- and ortho-phenolic sulfonamides is provided together with an overview of the chemistry of the products and their elaboration to building blocks for spirocyclic alkaloids. A concise total synthesis of putative lepadiformine complements the discussion. Making building blocks: The oxidative dearomatization of para- and ortho-phenolic sulfonamides provides building blocks for spirocyclic alkaloids (see scheme). The chemistry of the products of this reaction and a concise total synthesis of putative lepadiformine is given.
Efficient oxidative spirocyclization of phenolic sulfonamides
Canesi, Sylvain,Belmont, Philippe,Bouchu, Denis,Rousset, Laurence,Ciufolini, Marco A
, p. 5193 - 5195 (2007/10/03)
Treatment of various homotyramine sulfonamides with iodobenzene diacetate in hexafluoroisopropanol induces oxidative spirocyclization in high yield.
