477351-57-8Relevant academic research and scientific papers
Total synthesis and structural confirmation of chlorodysinosin A
Hanessian, Stephen,Del Valle, Juan R.,Xue, Yafeng,Blomberg, Niklas
, p. 10491 - 10495 (2007/10/03)
The first enantiocontrolled total synthesis of the marine sponge metabolite chlorodysinosin A is described. The structure and absolute configuration are identical to those of dysinosin A except for the presence of a novel 2S,3R-3-chloroleucine residue in
Total synthesis and structural confirmation of the marine natural product dysinosin A: A novel inhibitor of thrombin and Factor VIIa
Hanessian, Stephen,Margarita, Roberto,Hall, Adrian,Johnstone, Shawn,Tremblay, Martin,Parlanti, Luca
, p. 13342 - 13343 (2007/10/03)
The structure and absolute configuration of the marine antithrombotic product dysinosin A was confirmed by total synthesis. The strategy involved disconnections to three subunits, of which two were synthesized from the readily available l-glutamic acid, d
