477482-92-1Relevant academic research and scientific papers
Transition-metal-free direct amination of simple arenes with sulfonyl azides
Wang, Lianggui,Borah, Arun Jyoti,Yan, Guobing
, p. 1353 - 1355 (2015/03/04)
A metal-free green protocol has been developed for amination of simple arenes using arylsulfonyl azides via a nitrene transfer process under solvent free conditions at 130 °C releasing N2 gas as the sole by-product.
Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120)
Sparks, Steven M.,Chen, Grace,Collins, Jon L.,Danger, Dana,Dock, Steven T.,Jayawickreme, Channa,Jenkinson, Stephen,Laudeman, Christopher,Leesnitzer, M. Anthony,Liang, Xi,Maloney, Patrick,McCoy, David C.,Moncol, David,Rash, Vincent,Rimele, Thomas,Vulimiri, Padmaja,Way, James M.,Ross, Sean
, p. 3100 - 3103 (2014/06/24)
The exploration of a diarylsulfonamide series of free fatty acid receptor 4 (FFA4/GPR120) agonists is described. This work led to the identification of selective FFA4 agonist 8 (GSK137647A) and selective FFA4 antagonist 39. The in vitro profile of compounds 8 and 39 is presented herein.
Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120)
Sparks, Steven M.,Chen, Grace,Collins, Jon L.,Danger, Dana,Dock, Steven T.,Jayawickreme, Channa,Jenkinson, Stephen,Laudeman, Christopher,Leesnitzer, M. Anthony,Liang, Xi,Maloney, Patrick,McCoy, David C.,Moncol, David,Rash, Vincent,Rimele, Thomas,Vulimiri, Padmaja,Way, James M.,Ross, Sean
, p. 3100 - 3103 (2015/02/05)
The exploration of a diarylsulfonamide series of free fatty acid receptor 4 (FFA4/GPR120) agonists is described. This work led to the identification of selective FFA4 agonist 8 (GSK137647A) and selective FFA4 antagonist 39. The in vitro profile of compounds 8 and 39 is presented herein.
