477577-18-7

Usage

General Description

1-Pyrrolidineethanamine,3-fluoro-(9CI) is a chemical compound with the molecular formula C5H10FN. It is a derivative of 1-pyrrolidineethanamine and contains a fluorine atom. 1-Pyrrolidineethanamine,3-fluoro-(9CI) is commonly used in the field of pharmaceutical research and development as a building block for the synthesis of various biologically active molecules. It may also be used as a precursor in the production of other fluorinated compounds. Additionally, 1-Pyrrolidineethanamine,3-fluoro-(9CI) is known for its potential pharmacological activities and may have applications in the development of new drugs for various therapeutic purposes. 1-Pyrrolidineethanamine,3-fluoro-(9CI) should be handled with care and in accordance with proper safety precautions due to its potential hazards.

Relevant academic research and scientific papers

GLUCOPYRANOSYL DERIVATIVE AND USE THEREOF

The present invention relates to a glucopyranosyl derivative and a use thereof. In particular, the present invention relates to a glucopyranosyl derivative that is used as an inhibitor of sodium-dependent glucose transporters (SGLTs), particularly being used as an inhibitor of sodium-dependent glucose transporter-1 (SGLT1), and a pharmaceutically acceptable salt or stereoisomer thereof, further relating to a pharmaceutical composition containing the derivative. The present invention further relates to a use of the compound and a pharmaceutical composition thereof in the preparation of a drug for treating diabetes and diabetes-related diseases.

AMIDO-SUBSTITUTED AZOLE COMPOUNDS

The present invention relates to amido-substituted azole compounds of general formula (I), in which X1, X2, R1, R2, R4, R5, R7 and R8 are as defined in the claims which are inhibitors of TNKS1 and/or TNKS2, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.

PKM2 MODULATORS AND METHODS FOR THEIR USE

Compounds having activity as PKM2 activators are disclosed. The compounds have the following structure (I): including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein