477584-42-2

Basic information

• Product Name: Carbamic acid, (tetrahydro-3-oxo-2H-pyran-4-yl)-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, (tetrahydro-3-oxo-2H-pyran-4-yl)-, 1,1-dimethylethyl ester (9CI)
• CAS NO: 477584-42-2
• Molecular Formula: C10H17NO4
• Molecular Weight: 215.24628
• Product Categories: N-BOC
• Mol File: 477584-42-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 351.8±42.0 °C(Predicted)
• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• PKA: 10.85±0.20(Predicted)
• CAS DataBase Reference: Carbamic acid, (tetrahydro-3-oxo-2H-pyran-4-yl)-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (tetrahydro-3-oxo-2H-pyran-4-yl)-, 1,1-dimethylethyl ester (9CI)(477584-42-2)
• EPA Substance Registry System: Carbamic acid, (tetrahydro-3-oxo-2H-pyran-4-yl)-, 1,1-dimethylethyl ester (9CI)(477584-42-2)

Safety Data

• Hazardous Substances Data: 477584-42-2(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1096770-58-9 (3R,4S)-4-aminotetrahydro-2H-pyran-3-ol 
• 445480-33-1 tert-butyl [(3R,4S)-3-hydroxytetrahydro-2H-pyran-4-yl]carbamate 
• 445480-33-1 tert-butyl (trans-3-hydroxytetrahydro-2H-pyran-4-yl)carbamate 

Relevant articles and documents

NOVEL IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AS LRRK2 INHIBITORS

The present invention provides novel imidazo[4,5-c]quinoline derivatives of Formula (I), and the pharmaceutically acceptable salts thereof I wherein R1, R2 and R3 are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising the compounds of Formula I and to use of the compounds in the treatment of diseases associated with LRRK2, such as neurodegenerative diseases including Parkinson's disease or Alzheimer's disease, cancer, Crohn's disease or leprosy.