477587-43-2Relevant academic research and scientific papers
Highly enantioselective hydrogenation of β-alkyl and β-(ω-chloroalkyl) substituted β-keto esters
Karame, Iyad,Bellur, Esen,Rotzoll, Sven,Langer, Peter,Fischer, Christine,Holz, Jens,Boerner, Armin
, p. 1067 - 1076 (2007)
Highly enantioselective hydrogenation of β-alkyl and β-(ω-chloroalkyl) substituted β-keto esters was achieved with Ru catalysts based on chiral diphosphines in EtOH at 50°C under 50-bar initial hydrogen pressure, affording the corresponding β-hydroxy esters in >98% ee. Copyright Taylor & Francis Group, LLC.
