477722-22-8Relevant academic research and scientific papers
Lewis base activation of Lewis acids. Addition of silyl ketene acetals to aldehydes
Denmark, Scott E.,Wynn, Thomas,Beutner, Gregory L.
, p. 13405 - 13407 (2002)
The weak Lewis acid silicon tetrachloride can be activated by catalytic amounts of the chiral bisphosphoramide (R,R)-3 to form a highly reactive, chiral trichlorosilyl cation which is an extremely effective promoter of aldol addition reactions between ald
Lewis base activation of Lewis acids: Catalytic, enantioselective addition of silyl ketene acetals to aldehydes
Denmark, Scott E.,Beutner, Gregory L.,Wynn, Thomas,Eastgate, Martin D.
, p. 3774 - 3789 (2007/10/03)
The concept of Lewis base activation of Lewis acids has been reduced to practice for catalysis of the aldol reaction of silyl ketene acetals and silyl dienol ethers with aldehydes. The weakly acidic species, silicon tetrachloride (SiCl4), can b
