477738-89-9Relevant academic research and scientific papers
Sulfonamidolactam inhibitors of coagulation factor Xa
Smallheer, Joanne M.,Wang, Shuaige,Laws, Mia L.,Nakajima, Suanne,Hu, Zilun,Han, Wei,Jacobson, Irina,Luettgen, Joseph M.,Rossi, Karen A.,Rendina, Alan R.,Knabb, Robert M.,Wexler, Ruth R.,Lam, Patrick Y.S.,Quan, Mimi L.
, p. 2428 - 2433 (2008/09/21)
As part of an effort to identify novel backups for previously reported pyrazole-based coagulation Factor Xa inhibitors, the pyrazole 5-carboxamide moiety was replaced by 3-(sulfonylamino)-2-piperidone. This led to the identification of a structurally dive
