477788-89-9

Upstream product

• 41202-77-1 1-(2,3-dichlorophenyl)piperazine 
• 477788-88-8 {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine 
• 367275-36-3 2-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}-1H-isoindole-1,3(2H)-dione 
• 189061-44-7 4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butylamine 

Relevant academic research and scientific papers

Synthesis and biological characterization of novel hybrid 7-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro- naphthalen-2-ol and their heterocyclic bioisosteric analogues for dopamine D2 and D3 receptors

In a recent preliminary communication we described the development of a series of hybrid molecules for the dopamine D2 and D3 receptor subtypes. The design of these compounds was based on combining pharmacophoric elements of aminotetralin and piperazine m

A novel series of hybrid compounds derived by combining 2-aminotetralin and piperazine fragments: Binding activity at D2 and D3 receptors

A series of 7-hydroxy-2-[N-alkyl-(N-(4-phenylpiperazine)-alkyl)amino]tetralins was developed based on a novel hybrid approach that combined 2-aminotetralin and arylpiperazine pharmacophoric moieties. Our preliminary study revealed that a four-methylene bu