477863-06-2Relevant academic research and scientific papers
Regiodivergent Iridium(III)-Catalyzed Diamination of Alkenyl Amides with Secondary Amines: Complementary Access to γ- Or δ-Lactams
Conway, John H.,Rovis, Tomislav
supporting information, p. 135 - 138 (2018/01/17)
Alkenyl N-pivaloylhydroxamates undergo an Ir(III)-catalyzed diamination of the alkene with simple exogenous secondary amines under extraordinarily mild reaction conditions. The regioselectivity of the diamination is controlled by the solvent and the electronics of the cyclopentadienyl (Cpx) ligand on Ir. On the basis of a set of mechanistic experiments, we propose that the relative rates of Ir(V)-nitrenoid formation versus attack on the amido-Ir-coordinated alkene by the exogenous amine determine the outcome of the reaction.
An energy efficient and facile synthesis of high molecular weight polyesters using ketenes
Wolffs, Martin,Kade, Matthew J.,Hawker, Craig J.
supporting information; scheme or table, p. 10572 - 10574 (2011/11/06)
A facile, ketene-based strategy for the synthesis of polyesters from stable Meldrum's acid monomers has been developed which overcomes many issues associated with traditional step-growth procedures. A significant increase in polymerization efficiency is o
Lewis base-promoted hydrosilylation of cyclic malonates: Synthesis of β-substituted aldehydes and γ-substituted amines
Frost, Christopher G.,Hartley, Benjamin C.
supporting information; experimental part, p. 3599 - 3602 (2009/09/05)
The Lewis base-promoted hydrosilylation of cyclic malonates provides a convenient synthesis of β-substituted aldehydes. No over-reduction to the primary alcohol is observed as the aldehyde functionality is protected until a subsequent hydrolysis step. The
