477871-83-3 Usage
Chemical structure
The compound has a complex structure consisting of an indole ring, an ethyl group, a methyl group, and a carboxylic acid ester.
Derivative
It is a derivative of pyrrole, which is a heterocyclic compound with a five-membered ring containing two nitrogen atoms.
Applications
The compound is commonly used in the synthesis of pharmaceutical compounds and may have various applications in the field of medicinal chemistry and drug development.
Biological activities
Due to its unique structure, the compound may exhibit potential biological activities that can be useful in the development of new drugs.
Safety protocols
It is important to handle and use 1-[2-(1H-INDOL-3-YL)-ETHYL]-2-METHYL-5-OXO-4,5-DIHYDRO-1H-PYRROLE-3-CARBOXYLIC ACID METHYL ESTER with care and according to proper safety protocols due to its chemical properties.
Molecular weight
The molecular weight of the compound can be calculated based on its molecular formula and the atomic weights of the constituent elements.
Solubility
The compound's solubility in different solvents can be determined experimentally and may vary depending on the solvent's polarity and the compound's functional groups.
Stability
The stability of the compound under different conditions, such as temperature, pH, and exposure to light, can be assessed to ensure its suitability for various applications.
Synthesis
The compound can be synthesized through various chemical reactions, involving the formation of the indole ring, the attachment of the ethyl group, and the esterification of the carboxylic acid group.
Purity
The purity of the compound can be determined using analytical techniques such as high-performance liquid chromatography (HPLC) or mass spectrometry (MS) to ensure its quality and suitability for further use.
Handling
Proper handling and use of the compound are essential to minimize the risk of exposure and potential hazards associated with its chemical properties. This includes wearing appropriate personal protective equipment (PPE) and following good laboratory practices.
Check Digit Verification of cas no
The CAS Registry Mumber 477871-83-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,7,8,7 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 477871-83:
(8*4)+(7*7)+(6*7)+(5*8)+(4*7)+(3*1)+(2*8)+(1*3)=213
213 % 10 = 3
So 477871-83-3 is a valid CAS Registry Number.
477871-83-3Relevant academic research and scientific papers
Enantioselective Bronsted acid-catalyzed N-acyliminium cyclization cascades
Muratore, Michael E.,Holloway, Chloe A.,Pilling, Adam W.,Storer, R. Ian,Trevitt, Graham,Dixon, Darren J.
supporting information; experimental part, p. 10796 - 10797 (2009/12/03)
(Chemical Equation Presented) An enantioselective Bronsted acid-catalyzed N-acyliminium cyclization cascade of tryptamines with enol lactones to form architecturally complex heterocycles in high enantiomeric excess has been developed. The reaction is technically simple to perform as well as atom-efficient and may be coupled to a gold(I)-catalyzed cycloisomerization of alkynoic acids whereby the key enol lactone reaction partner is generated in situ. Employing up to 10 mol % bulky chiral phosphoric acid catalysts in boiling toluene allowed the product materials to be generated in good overall yields (63-99%) and high enantioselectivities (72-99% ee). With doubly substituted enol lactones, high diastereo- and enantioselectivities were obtained, thus providing a new example of a dynamic kinetic asymmetric cyclization reaction.
