478159-02-3

Upstream product

• 85743-99-3 N-(2-Trimethylsilanyloxy-pyrimidin-4-yl)-benzamide 
• 478158-96-2 Acetic acid (3S,5S)-3-azido-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-thiophen-2-yl ester 
• 478158-91-7 (3S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-tetrahydro-thiophen-3-ol 
• 478158-94-0 ((2S,4S)-4-Azido-tetrahydro-thiophen-2-ylmethoxy)-tert-butyl-diphenyl-silane 
• 478158-93-9 (3R,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-tetrahydro-thiophen-3-ol 
• 478158-95-1 ((2S,4S)-4-Azido-1-oxo-tetrahydro-1λ⁴-thiophen-2-ylmethoxy)-tert-butyl-diphenyl-silane 
• 478158-92-8 Benzoic acid (3R,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-thiophen-3-yl ester 

Relevant academic research and scientific papers

Synthesis and biological evaluation of novel D-2′-azido-2′,3′-dideoxyarabinofuranosyl-4′- thiopyrimidines and purines

Novel D-2′-azido-2′,3′-dideoxyarabinofuranosyl-4′- thiopyrimidines and purines have been synthesized, starting from L-xylose via azidation at the 2′-position as a key step. Most of the final nucleosides exhibited toxicity-dependent anti-HIV-1 activity, among which D-α-adenine analogue 3h was found to be the most cytotoxic.