4782-25-6Relevant articles and documents
Structure, properties and cytostatic activity of triorganotin (aminoaryl)carboxylates
Pruchnik, Florian P.,Banbula, Malgorzata,Ciunik, Zbigniew,Chojnacki, Henryk,Latocha, Malgorzata,Skop, Barbara,Wilczok, Tadeusz,Opolski, Adam,Wietrzyk, Joanna,Nasulewicz, Anna
, p. 3214 - 3221 (2007/10/03)
The properties of vinyltin and phenyltin complexes [Sn(CH=CH2)3{μ-OOCC6H3 (NH2)2-3,4}]n (1), [Sn(C6H5)3- {OOCC6H3(NH2)2-3,4}] (2), [Sn(C6H5)3{OOC-2-C6H4 N= NC6H4N(CH3)2-4})] (3) and [Sn(CH=CH2)3{OOC-2-C6H4N= NC6H4N(CH3)2-4}] (4) have been investigated. The structures of complexes 1, 2, and 3, have been determined by X-ray crystallography, Compound 1 is a distorted trigonal-bipyramidal complex and compounds 2 and 3 adopt a distorted tetrahedral structure. Complex 1 is a single-strand polymer with a bridging 3,4-diaminobenzoato ligand coordinating via the O(1) atom of the carboxylato group and the nitrogen atom of the para-amino group. The oxygen and nitrogen atoms occupy the axial coordination sites. The Sn(1)-N(2A) bond is weak. In complexes 2 and 3 the carboxylato hgands are strongly coordinated to the central atom via one oxygen atom, and the Sn(1)-O(2) distances are considerably longer. Weak interactions of the central atom with the amino group in complex 1, and with the O(2) atoms in complexes 2 and 3, as well as the hydrogen bonds, stabilize the crystal structure. The complexes are effective cytostatic agents. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.
