478249-63-7 Usage
Derivative of pyrrole
The compound is a derivative of pyrrole, a heterocyclic aromatic compound, which means it is a modified version of pyrrole with additional functional groups.
Fluorobenzyl group
The compound contains a fluorobenzyl group, which is a benzyl group (a carbon-based group) that has a fluorine atom attached to it.
Amide functional group
The compound has an amide functional group, which is a carbonyl group (C=O) bonded to a nitrogen atom.
Potential applications in medicinal chemistry and drug development
1H-Pyrrole-2-carboxylic acid 4-fluoro-benzylamide may have potential applications in medicinal chemistry and drug development due to its ability to interact with biological targets through its amide bond and aromatic ring.
Specific properties and potential uses depend on further research
The specific properties and potential uses of 1H-Pyrrole-2-carboxylic acid 4-fluoro-benzylamide would need to be further explored and researched to determine its full potential.
Check Digit Verification of cas no
The CAS Registry Mumber 478249-63-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,2,4 and 9 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 478249-63:
(8*4)+(7*7)+(6*8)+(5*2)+(4*4)+(3*9)+(2*6)+(1*3)=197
197 % 10 = 7
So 478249-63-7 is a valid CAS Registry Number.
478249-63-7Relevant academic research and scientific papers
Silvestri, Romano,La Regina, Giuseppe,De Martino, Gabriella,Artico, Marino,Befani, Olivia,Palumbo, Marianna,Agostinelli, Enzo,Turini, Paola
, p. 917 - 920 (2003)
N-Benzyl- and N-propargyl-1H-pyrrole-2-carboxyamides and some related methylenamines were synthesized and tested for their monoamine oxidase types A and B inhibitory activity. 2-(N-Methyl-N-propargylaminomethyl)-1H-pyrrole (24) was the most potent MAO-A inhibitor of the series [Ki(MAO-A) = 0.0054 μM], but it was not selective. Inhibitors N-4-fluorobenzyl-1H-pyrrole-2-carboxamide (12) and N-cyclohexylmethyl-1H-pyrrole-2-carboxamide (25) showed the highest MAO-A selectivity indexes (SI) corresponding to 2025 and > 2500, respectively, while 2-(N-methyl-N-benzylaminomethyl)-1H-pyrrole (21) was the most selective MAO-B inhibitor, having an SI of 0.0057.
